HRASLS5 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | Q96KN8 |
Other Accession | NP_473449.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 30312 Da |
Antigen Region | 100-129 aa |
Gene ID | 117245 |
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Other Names | Ca(2+)-independent N-acyltransferase, iNAT, 231-, H-rev107-like protein 5, HRAS-like suppressor 5, HRSL5, HRASLS5, HRLP5 |
Target/Specificity | This HRASLS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the Central region of human HRASLS5. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HRASLS5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PLAAT5 (HGNC:24978) |
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Synonyms | HRASLS5, HRLP5 |
Function | Exhibits both phospholipase A1/2 and acyltransferase activities (PubMed:22825852, PubMed:26503625). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (PubMed:22825852). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs) (PubMed:19000777, PubMed:22825852). |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q4KLN5} |
Tissue Location | Highest expression level in testis and pancreas. |
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Provided below are standard protocols that you may find useful for product applications.
References
Jin, X.H., et al. Biochim. Biophys. Acta 1791(1):32-38(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Jin, X.H., et al. J. Biol. Chem. 282(6):3614-3623(2007)
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