EDN2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P20800 |
Other Accession | Q28470, NP_001947.1 |
Reactivity | Human |
Predicted | Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 19960 Da |
Antigen Region | 107-136 aa |
Gene ID | 1907 |
---|---|
Other Names | Endothelin-2, ET-2, Preproendothelin-2, PPET2, EDN2 |
Target/Specificity | This EDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the C-terminal region of human EDN2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | EDN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EDN2 |
---|---|
Function | Endothelins are endothelium-derived vasoconstrictor peptides. |
Cellular Location | Secreted. |
Tissue Location | Expressed in lung, but not in placental stem villi vessels or cultured placental villi smooth muscle cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. [provided by RefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Darrah, R., et al. Physiol. Genomics 41(1):71-77(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :
Wiesmann, F., et al. Breast Cancer Res. 11 (3), R34 (2009) :
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