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CD7 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P09564 |
| Other Accession | NP_006128.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 25409 Da |
| Antigen Region | 63-92 aa |
| Gene ID | 924 |
|---|---|
| Other Names | T-cell antigen CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, CD7, CD7 |
| Target/Specificity | This CD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the Central region of human CD7. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CD7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CD7 |
|---|---|
| Function | Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors (PubMed:7506726). Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1 (PubMed:10652336). In turn, mediates the production of cytokines such as IL-2 (PubMed:1709867). On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels (PubMed:7506726). |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Location | Expressed on T-cells and natural killer (NK) cells and their precursors. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.
References
Rohrs, S., et al. J Hematol Oncol 3, 15 (2010) :
Rogers, S.L., et al. Mol. Cancer 9, 41 (2010) :
Koh, H.S., et al. Mol. Cells 28(6):553-558(2009)
Yoo, E.H., et al. Korean J Lab Med 29(6):491-496(2009)
SundarRaj, S., et al. Mol. Immunol. 46(16):3411-3419(2009)
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