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PODXL2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NZ53 |
| Other Accession | NP_056535.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 65076 Da |
| Antigen Region | 573-602 aa |
| Gene ID | 50512 |
|---|---|
| Other Names | Podocalyxin-like protein 2, Endoglycan, PODXL2 |
| Target/Specificity | This PODXL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-602 amino acids from the C-terminal region of human PODXL2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PODXL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PODXL2 |
|---|---|
| Function | Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins. |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Endoglycan is a disulfide-linked homodimeric membrane protein belongong to the podocalyxin family.
References
Kerr, S.C., et al. J. Immunol. 181(2):1480-1490(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Fieger, C.B., et al. J. Biol. Chem. 278(30):27390-27398(2003)
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