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PODXL2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PODXL2 Antibody (C-term) AP13602B
    PODXL2 Antibody (C-term) (Cat. #AP13602b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PODXL2 antibody detected the PODXL2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NZ53
Other Accession NP_056535.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 65076 Da
Antigen Region 573-602 aa
Additional Information
Gene ID 50512
Other Names Podocalyxin-like protein 2, Endoglycan, PODXL2
Target/Specificity This PODXL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-602 amino acids from the C-terminal region of human PODXL2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPODXL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PODXL2
Function Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells
Research Areas
Citations (0)
citation

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Background

Endoglycan is a disulfide-linked homodimeric membrane protein belongong to the podocalyxin family.

References

Kerr, S.C., et al. J. Immunol. 181(2):1480-1490(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Fieger, C.B., et al. J. Biol. Chem. 278(30):27390-27398(2003)

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$ 365.00
$ 140.00
Cat# AP13602B
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