TSPYL5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q86VY4 |
Other Accession | NP_277047.2 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 45143 Da |
Antigen Region | 344-372 aa |
Gene ID | 85453 |
---|---|
Other Names | Testis-specific Y-encoded-like protein 5, TSPY-like protein 5, TSPYL5, KIAA1750 |
Target/Specificity | This TSPYL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-372 amino acids from the C-terminal region of human TSPYL5. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TSPYL5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TSPYL5 |
---|---|
Synonyms | KIAA1750 |
Function | Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Kim, E.J., et al. Biochem. Biophys. Res. Commun. 392(3):448-453(2010)
Jung, Y., et al. Lab. Invest. 88(2):153-160(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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