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BNIP2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q12982 |
| Other Accession | NP_004321.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36018 Da |
| Antigen Region | 285-316 aa |
| Gene ID | 663 |
|---|---|
| Other Names | BCL2/adenovirus E1B 19 kDa protein-interacting protein 2, BNIP2, NIP2 |
| Target/Specificity | This BNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-316 amino acids from the C-terminal region of human BNIP2. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BNIP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BNIP2 |
|---|---|
| Synonyms | NIP2 |
| Function | Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins. |
| Cellular Location | Cytoplasm. Cytoplasm, perinuclear region. Note=Localizes to the nuclear envelope region and to other cytoplasmic structures |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. Though the specific function is unknown, it interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector.
References
Scott, G.B., et al. Biochem. J. 431(3):423-431(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Valencia, C.A., et al. Biochem. Biophys. Res. Commun. 364(3):495-501(2007)
Zhou, Y.T., et al. Exp. Cell Res. 303(2):263-274(2005)
Shang, X., et al. J. Biol. Chem. 278(46):45903-45914(2003)
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