SPT19 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q7Z5L4 |
Other Accession | NP_777587.1 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 19186 Da |
Antigen Region | 122-150 aa |
Gene ID | 219938 |
---|---|
Other Names | Spermatogenesis-associated protein 19, mitochondrial, Spermatogenic cell-specific gene 1 protein, Spergen-1, SPATA19, SPERGEN1 |
Target/Specificity | This SPT19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-150 amino acids from the C-terminal region of human SPT19. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SPT19 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SPATA19 |
---|---|
Synonyms | SPERGEN1 |
Function | Essential for sperm motility and male fertility (By similarity). Plays an important role in sperm motility by regulating the organization and function of the mitochondria and is also required for correct sperm midpiece assembly (By similarity). |
Cellular Location | Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9DAQ9}. Mitochondrion {ECO:0000250|UniProtKB:Q9DAQ9}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9DAQ9}. Note=Localizes to the midpiece of the sperm flagellum. {ECO:0000250|UniProtKB:Q9DAQ9} |
Tissue Location | Expressed specifically in testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
SPT19 may have a role in spermiogenesis.
References
Ghafouri-Fard, S., et al. Br. J. Dermatol. 162(4):772-779(2010)
Stolk, L., et al. Nat. Genet. 41(6):645-647(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.