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ADSS Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P30520 |
| Other Accession | NP_001117.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50097 Da |
| Antigen Region | 396-422 aa |
| Gene ID | 159 |
|---|---|
| Other Names | Adenylosuccinate synthetase isozyme 2 {ECO:0000255|HAMAP-Rule:MF_03127}, AMPSase 2 {ECO:0000255|HAMAP-Rule:MF_03127}, AdSS 2 {ECO:0000255|HAMAP-Rule:MF_03127}, 6344 {ECO:0000255|HAMAP-Rule:MF_03127}, Adenylosuccinate synthetase, acidic isozyme {ECO:0000255|HAMAP-Rule:MF_03127}, Adenylosuccinate synthetase, liver isozyme {ECO:0000255|HAMAP-Rule:MF_03127}, L-type adenylosuccinate synthetase {ECO:0000255|HAMAP-Rule:MF_03127}, IMP--aspartate ligase 2 {ECO:0000255|HAMAP-Rule:MF_03127}, ADSS {ECO:0000255|HAMAP-Rule:MF_03127} |
| Target/Specificity | This ADSS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-422 amino acids from the C-terminal region of human ADSS. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ADSS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADSS2 (HGNC:292) |
|---|---|
| Function | Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. |
| Cellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03127}. Mitochondrion {ECO:0000250|UniProtKB:A4Z6H1}. Note=Partially associated with particulate fractions |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.
References
Sivendran, S., et al. Protein Sci. 17(7):1162-1174(2008)
Zhang, F., et al. BMC Med. Genet. 9, 119 (2008) :
Zhang, F., et al. Behav Brain Funct 4, 39 (2008) :
Sun, H., et al. Mol. Cell. Biochem. 269 (1-2), 85-94 (2005) :
Stepinski, J., et al. Kidney Int. 50(4):1195-1201(1996)
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