ARPP-21 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9UBL0 |
Other Accession | Q9DCB4, NP_001020239.1, NP_001020240.1, NP_938409.1, NP_057384.2 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 89196 Da |
Antigen Region | 85-114 aa |
Gene ID | 10777 |
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Other Names | cAMP-regulated phosphoprotein 21, ARPP-21, Thymocyte cAMP-regulated phosphoprotein, ARPP21, TARPP |
Target/Specificity | This ARPP-21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human ARPP-21. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ARPP-21 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ARPP21 |
---|---|
Synonyms | TARPP |
Function | Isoform 2 may act as a competitive inhibitor of calmodulin- dependent enzymes such as calcineurin in neurons. |
Cellular Location | Cytoplasm. |
Tissue Location | Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
Background
Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons (By similarity).
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Brill, L.M., et al. Anal. Chem. 76(10):2763-2772(2004)
Brill, L.M., et al. Anal. Chem. 76(10):2763-2772(2004)
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