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GCC1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q96CN9 |
| Other Accession | NP_078799.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 87811 Da |
| Antigen Region | 671-700 aa |
| Gene ID | 79571 |
|---|---|
| Other Names | GRIP and coiled-coil domain-containing protein 1, Golgi coiled-coil protein 1, GCC1 |
| Target/Specificity | This GCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-700 amino acids from the C-terminal region of human GCC1. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GCC1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GCC1 |
|---|---|
| Function | Probably involved in maintaining Golgi structure. |
| Cellular Location | Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq].
References
Lieu, Z.Z., et al. Mol. Biol. Cell 18(12):4979-4991(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Luke, M.R., et al. Biochem. J. 388 (PT 3), 835-841 (2005) :
Luke, M.R., et al. J. Biol. Chem. 278(6):4216-4226(2003)
Kjer-Nielsen, L., et al. Curr. Biol. 9(7):385-388(1999)
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