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CEBPD Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - CEBPD Antibody (C-term) AP12648b
    CEBPD Antibody (C-term) (Cat. #AP12648b) western blot analysis in SH-SY5Y cell line lysates (35ug/lane).This demonstrates the CEBPD antibody detected the CEBPD protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P49716
Other Accession Q03484, Q00322, O02756, NP_005186.2, Q9N0J3
Reactivity Human
Predicted Bovine, Mouse, Rat, Sheep
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 28467 Da
Antigen Region 169-197 aa
Additional Information
Gene ID 1052
Other Names CCAAT/enhancer-binding protein delta, C/EBP delta, Nuclear factor NF-IL6-beta, NF-IL6-beta, CEBPD
Target/Specificity This CEBPD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the C-terminal region of human CEBPD.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCEBPD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CEBPD
Function Transcription activator that recognizes two different DNA motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers (PubMed:16397300). Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:16397300, PubMed:1741402). Transcriptional activator that enhances IL6 transcription alone and as heterodimer with CEBPB (PubMed:1741402).
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11.

References

Zannetti, C., et al. J. Biol. Chem. 285(45):34773-34780(2010)
Wang, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(37):16131-16136(2010)
Hour, T.C., et al. Biochem. Pharmacol. 80(3):325-334(2010)
Bennett, C.E., et al. Diab Vasc Dis Res 7(3):195-203(2010)
Payne, V.A., et al. Biochem. J. 425(1):215-223(2010)

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$ 365.00
$ 140.00
Cat# AP12648b
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