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GPD2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P43304 |
| Other Accession | Q64521, Q4R755, A6QLU1 |
| Reactivity | Human |
| Predicted | Bovine, Monkey, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 80853 Da |
| Antigen Region | 606-634 aa |
| Gene ID | 2820 |
|---|---|
| Other Names | Glycerol-3-phosphate dehydrogenase, mitochondrial, GPD-M, GPDH-M, mtGPD, GPD2 |
| Target/Specificity | This GPD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 606-634 amino acids from the C-terminal region of human GPD2. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GPD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPD2 (HGNC:4456) |
|---|---|
| Function | Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta- cell glucose-sensing device. |
| Cellular Location | Mitochondrion. |
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.
References
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
Daoud, H., et al. Hum. Genet. 124(6):649-658(2009)
Chowdhury, S.K., et al. Free Radic. Res. 41(10):1116-1124(2007)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
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