STX5 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q13190 |
Other Accession | Q08DB5, NP_003155.2 |
Reactivity | Human, Mouse |
Predicted | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 39673 Da |
Antigen Region | 180-209 aa |
Gene ID | 6811 |
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Other Names | Syntaxin-5, STX5, STX5A |
Target/Specificity | This STX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-209 amino acids from the Central region of human STX5. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | STX5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STX5 |
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Synonyms | STX5A |
Function | Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter- connected structure of the Golgi apparatus. |
Cellular Location | Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:Q08851}; Single-pass type IV membrane protein. Golgi apparatus membrane. Note=Localizes throughout the Golgi apparatus, but most abundant in the cis-most cisternae |
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Provided below are standard protocols that you may find useful for product applications.
Background
STX5 mediates endoplasmic reticulum to Golgi transport (By similarity).
References
Laufman, O., et al. EMBO J. 28(14):2006-2017(2009)
Diao, A., et al. J. Biol. Chem. 283(11):6957-6967(2008)
Amessou, M., et al. J. Cell. Sci. 120 (PT 8), 1457-1468 (2007) :
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Suga, K., et al. FEBS Lett. 579(20):4226-4234(2005)
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