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FGF22 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FGF22 Antibody (N-term) AP12191A
    FGF22 Antibody (N-term) (Cat. #AP12191a) western blot analysis in MDA-MB231,K562,293,CEM cell line lysates (35ug/lane).This demonstrates the FGF22 antibody detected the FGF22 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9HCT0
Other Accession Q9ESS2, NP_065688.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 19663 Da
Antigen Region 18-46 aa
Additional Information
Gene ID 27006
Other Names Fibroblast growth factor 22, FGF-22, FGF22
Target/Specificity This FGF22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human FGF22.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFGF22 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FGF22
Function Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. [provided by RefSeq].

References

Moffa, A.B., et al. J. Cell. Physiol. 210(3):720-731(2007)
Zhang, X., et al. J. Biol. Chem. 281(23):15694-15700(2006)
Beer, H.D., et al. Oncogene 24(34):5269-5277(2005)
Popovici, C., et al. J. Biol. Chem. 279(38):40146-40152(2004)
Umemori, H., et al. Cell 118(2):257-270(2004)

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$ 365.00
$ 140.00
Cat# AP12191A
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