PCYT1A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IF, IHC-P, WB, E |
---|---|
Primary Accession | P49585 |
Other Accession | P19836, P49586, P49584, NP_005008.2 |
Reactivity | Human |
Predicted | Hamster, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 41731 Da |
Antigen Region | 27-54 aa |
Gene ID | 5130 |
---|---|
Other Names | Choline-phosphate cytidylyltransferase A, CCT-alpha, CTP:phosphocholine cytidylyltransferase A, CCT A, CT A, Phosphorylcholine transferase A, PCYT1A, CTPCT, PCYT1 |
Target/Specificity | This PCYT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human PCYT1A. |
Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PCYT1A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PCYT1A |
---|---|
Synonyms | CTPCT, PCYT1 |
Function | Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:P19836}. Membrane {ECO:0000250|UniProtKB:P19836}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19836}. Endoplasmic reticulum. Nucleus Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form. {ECO:0000250|UniProtKB:P19836} |
Tissue Location | Brain, placenta, liver, fetal and adult lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PCYT1A controls phosphatidylcholine synthesis.
References
Mostowska, A., et al. J. Med. Genet. (2010) In press :
Mostowska, A., et al. Eur. J. Oral Sci. 118(4):325-332(2010)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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