FAH Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF, IHC-P, E |
---|---|
Primary Accession | P16930 |
Other Accession | NP_000128 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 46374 Da |
Antigen Region | 7-33 aa |
Gene ID | 2184 |
---|---|
Other Names | Fumarylacetoacetase, FAA, Beta-diketonase, Fumarylacetoacetate hydrolase, FAH |
Target/Specificity | This FAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-33 amino acids from the N-terminal region of human FAH. |
Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FAH Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FAH |
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Tissue Location | Mainly expressed in liver and kidney. Lower levels are also detected in many other tissues |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT).
References
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Liu, J., et al. Hum Brain Mapp 30(1):241-255(2009)
Ferreira, M.A., et al. Nat. Genet. 40(9):1056-1058(2008)
Bliksrud, Y.T., et al. J. Mol. Med. 83(5):406-410(2005)
Dreumont, N., et al. BMC Mol. Biol. 6 (1), 1 (2005) :
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