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TUBB6 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BUF5 |
| Other Accession | Q9D6F9, Q4R4X8, P04350, Q3ZBU7, NP_115914.1 |
| Reactivity | Human |
| Predicted | Bovine, Monkey, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49857 Da |
| Antigen Region | 139-166 aa |
| Gene ID | 84617 |
|---|---|
| Other Names | Tubulin beta-6 chain, Tubulin beta class V, TUBB6 |
| Target/Specificity | This TUBB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-166 amino acids from the Central region of human TUBB6. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TUBB6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TUBB6 |
|---|---|
| Function | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. |
| Cellular Location | Cytoplasm, cytoskeleton. |
| Tissue Location | Ubiquitous. Maximal expression in breast and lung, where it represents around 10% of all beta-tubulins. Largely decreased expression in most cancerous tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain (By similarity).
References
Leandro-Garcia, L.J., et al. Cytoskeleton (Hoboken) 67(4):214-223(2010)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
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