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FGF16 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O43320 |
| Other Accession | O54769, Q9ESL8, NP_003859.1 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 23759 Da |
| Antigen Region | 22-50 aa |
| Gene ID | 8823 |
|---|---|
| Other Names | Fibroblast growth factor 16, FGF-16, FGF16 |
| Target/Specificity | This FGF16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human FGF16. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FGF16 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FGF16 |
|---|---|
| Function | Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:O54769}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The rat homolog is predominantly expressed in embryonic brown adipose tissue and has significant mitogenic activity, which suggests a role in proliferation of embryonic brown adipose tissue.
References
Sofronescu, A.G., et al. Cardiovasc. Res. 87(1):102-110(2010)
Moffa, A.B., et al. J. Cell. Physiol. 210(3):720-731(2007)
Antoine, M., et al. Biochem. Biophys. Res. Commun. 346(1):224-233(2006)
Zhang, X., et al. J. Biol. Chem. 281(23):15694-15700(2006)
Popovici, C., et al. J. Biol. Chem. 279(38):40146-40152(2004)
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