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ADCY2 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q08462 |
| Other Accession | P26769, Q80TL1, NP_065433.2 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 123603 Da |
| Antigen Region | 451-481 aa |
| Gene ID | 108 |
|---|---|
| Other Names | Adenylate cyclase type 2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, ADCY2, KIAA1060 |
| Target/Specificity | This ADCY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-481 amino acids from the Central region of human ADCY2. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ADCY2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADCY2 |
|---|---|
| Synonyms | KIAA1060 |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (By similarity). |
| Cellular Location | Membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm |
| Tissue Location | Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699). Expressed in brain, especially in caudate nucleus, cerebellum and hippocampus |
Research Areas
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$ 192.50
Cat# AP11322c
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