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PIP5KL1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, IHC-P, E |
|---|---|
| Primary Accession | Q5T9C9 |
| Other Accession | NP_001128691.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 44572 Da |
| Antigen Region | 57-86 aa |
| Gene ID | 138429 |
|---|---|
| Other Names | Phosphatidylinositol 4-phosphate 5-kinase-like protein 1, PI(4)P 5-kinase-like protein 1, PtdIns(4)P-5-kinase-like protein 1, PIP5KL1 |
| Target/Specificity | This PIP5KL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-86 amino acids from the N-terminal region of human PIP5KL1. |
| Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PIP5KL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PIP5KL1 |
|---|---|
| Function | May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3. |
| Cellular Location | Cytoplasm. Membrane. Note=Localized to large cytoplasmic vesicular structures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PIP5KL1 is a phosphoinositide kinase-like protein that lacks intrinsic lipid kinase activity but associates with type I PIPKs (see PIP5K1A; MIM 603275) and may play a role in localization of PIPK activity (Chang et al., 2004 [PubMed 14701839]).[supplied by OMIM].
References
Shi, L., et al. Mol. Biol. Rep. 37(5):2189-2198(2010)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Chang, J.D., et al. J. Biol. Chem. 279(12):11672-11679(2004)
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