PMPCA Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
---|---|
Primary Accession | Q10713 |
Other Accession | NP_055975.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 58253 Da |
Antigen Region | 454-483 aa |
Gene ID | 23203 |
---|---|
Other Names | Mitochondrial-processing peptidase subunit alpha, Alpha-MPP, P-55, PMPCA, INPP5E, KIAA0123, MPPA |
Target/Specificity | This PMPCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of human PMPCA. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PMPCA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PMPCA |
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Synonyms | INPP5E, KIAA0123, MPPA |
Function | Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. |
Cellular Location | Mitochondrion matrix {ECO:0000250|UniProtKB:P20069}. Mitochondrion inner membrane |
Tissue Location | Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis |
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Provided below are standard protocols that you may find useful for product applications.
References
Hassel, S., et al. Proteomics 4(5):1346-1358(2004)
Harris, R.A., et al. Proteomics 2(2):212-223(2002)
Nagao, Y., et al. J. Biol. Chem. 275(44):34552-34556(2000)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
Luciano, P., et al. J. Mol. Biol. 272(2):213-225(1997)
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