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CLEC11A Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CLEC11A Antibody (Center) AP11087C
    Western blot analysis of CLEC11A (arrow) using rabbit polyclonal CLEC11A Antibody (Center) (Cat. #AP11087c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLEC11A gene.
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  • IHC-P - CLEC11A Antibody (Center) AP11087C
    CLEC11A Antibody (Center) (Cat. #AP11087c)immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLEC11A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - CLEC11A Antibody (Center) AP11087C
    CLEC11A Antibody (Center) (Cat. #AP11087c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
  • SPECIFICATION
  • CITATIONS: 1
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, FC, E
Primary Accession Q9Y240
Other Accession NP_002966.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35695 Da
Antigen Region 145-174 aa
Additional Information
Gene ID 6320
Other Names C-type lectin domain family 11 member A, C-type lectin superfamily member 3, Lymphocyte secreted C-type lectin, Stem cell growth factor, p47, CLEC11A, CLECSF3, LSLCL, SCGF
Target/Specificity This CLEC11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human CLEC11A.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLEC11A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLEC11A
Synonyms CLECSF3, LSLCL, SCGF
Function Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts (PubMed:27976999). Important for repair and maintenance of adult bone (By similarity).
Cellular Location Cytoplasm. Secreted
Tissue Location Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver
Research Areas
Citations ( 0 )

Background

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.

References

Ouma, C., et al. Infect. Immun. 78(1):453-460(2010)
Keller, C.C., et al. Infect. Immun. 77(9):3864-3871(2009)
Lan, C.C., et al. Br. J. Dermatol. 160(6):1180-1187(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hollenbeck, S.T., et al. J. Surg. Res. 120(2):288-294(2004)

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$ 365.00
$ 140.00
Cat# AP11087C
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