BCL7A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q4VC05 |
Other Accession | Q5XH61, Q9CXE2, Q5XFY4, NP_001019979.1, NP_066273.1 |
Reactivity | Human |
Predicted | Zebrafish, Mouse, Xenopus |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 22810 Da |
Antigen Region | 1-30 aa |
Gene ID | 605 |
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Other Names | B-cell CLL/lymphoma 7 protein family member A, BCL7A |
Target/Specificity | This BCL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BCL7A. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | BCL7A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BCL7A |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
References
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Liang, X.S., et al. Br. J. Haematol. 146(4):418-423(2009)
Morton, L.M., et al. Cancer Epidemiol. Biomarkers Prev. 18(4):1259-1270(2009)
Carbone, A., et al. Genes Chromosomes Cancer 47(12):1067-1075(2008)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
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