CT117 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, E |
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Primary Accession | O94964 |
Other Accession | NP_542194.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 183858 Da |
Antigen Region | 97-125 aa |
Gene ID | 140710 |
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Other Names | Protein SOGA1, SOGA family member 1, Suppressor of glucose by autophagy, Suppressor of glucose, autophagy-associated protein 1, N-terminal form, C-terminal 80 kDa form, 80-kDa SOGA fragment, SOGA1, C20orf117, KIAA0889, SOGA |
Target/Specificity | This CT117 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-125 amino acids from the N-terminal region of human CT117. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CT117 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MTCL2 (HGNC:16111) |
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Function | Microtubule-associated factor that enables integration of the centrosomal and Golgi-associated microtubules on the Golgi membrane, supporting directional migration. Preferentially acts on the perinuclear microtubules accumulated around the Golgi. Associates with the Golgi membrane through the N-terminal coiled-coil region and directly binds microtubules through the C-terminal domain (By similarity). Required for faithful chromosome segregation during mitosis (PubMed:33587225). Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin- dependent manner (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton. Golgi apparatus membrane {ECO:0000250|UniProtKB:E1U8D0}. Midbody Note=Associates with microtubules during late mitosis and interphase |

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Provided below are standard protocols that you may find useful for product applications.
References
Brajenovic, M., et al. J. Biol. Chem. 279(13):12804-12811(2004)

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