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MTX2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - MTX2 Antibody  (C-term) AP10797b
    MTX2 Antibody (C-term) (Cat. #AP10797b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the MTX2 antibody detected the MTX2 protein (arrow).
    detail
  • IHC-P - MTX2 Antibody  (C-term) AP10797b
    MTX2 Antibody (C-term) (Cat. #AP10797b) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MTX2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - MTX2 Antibody  (C-term) AP10797b
    MTX2 Antibody (C-term) (Cat. #AP10797b) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession O75431
Other Accession NP_006545.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 29763 Da
Antigen Region 232-261 aa
Additional Information
Gene ID 10651
Other Names Metaxin-2, Mitochondrial outer membrane import complex protein 2, MTX2
Target/Specificity This MTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human MTX2.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMTX2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTX2
Function Involved in transport of proteins into the mitochondrion.
Cellular Location Mitochondrion outer membrane. Mitochondrion
Research Areas
Citations (0)
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Background

The protein encoded by this gene is highly similar to the metaxin 2 protein from mouse, which has been shown to interact with the mitochondrial membrane protein metaxin 1. Because of this similarity, it is thought that the encoded protein is peripherally associated with the cytosolic face of the outer mitochondrial membrane, and that it is involved in the import of proteins into the mitochondrion. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Xie, J., et al. FEBS Lett. 581(18):3545-3549(2007)
Kozjak-Pavlovic, V., et al. EMBO Rep. 8(6):576-582(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Armstrong, L.C., et al. J. Cell. Biochem. 74(1):11-22(1999)

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$ 182.50
$ 70.00
Cat# AP10797b
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