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NDUFC2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O95298 |
| Other Accession | NP_004540.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 14188 Da |
| Antigen Region | 90-119 aa |
| Gene ID | 4718 |
|---|---|
| Other Names | NADH dehydrogenase [ubiquinone] 1 subunit C2, Complex I-B145b, CI-B145b, Human lung cancer oncogene 1 protein, HLC-1, NADH-ubiquinone oxidoreductase subunit B145b, NDUFC2 |
| Target/Specificity | This NDUFC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the C-terminal region of human NDUFC2. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NDUFC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NDUFC2 (HGNC:7706) |
|---|---|
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side |
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Provided below are standard protocols that you may find useful for product applications.
Background
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
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