RPH3AL Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q9UNE2 |
Other Accession | NP_008918.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 34464 Da |
Antigen Region | 208-237 aa |
Gene ID | 9501 |
---|---|
Other Names | Rab effector Noc2, No C2 domains protein, Rabphilin-3A-like protein, RPH3AL, NOC2 |
Target/Specificity | This RPH3AL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the C-terminal region of human RPH3AL. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RPH3AL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RPH3AL |
---|---|
Synonyms | NOC2 |
Function | Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells. |
Cellular Location | Cytoplasm. Cytoplasmic vesicle, secretory vesicle membrane. Note=Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells |
Tissue Location | Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver Also detected in epithelial cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene plays a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells and plays a key role in insulin secretion by pancreatic cells. This gene is likely a tumor suppressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press : Shanmugam, C., et al. Biotech Histochem 84(2):39-45(2009) Katkoori, V.R., et al. Front. Biosci. 13, 1050-1061 (2008) : Matsumoto, M., et al. Proc. Natl. Acad. Sci. U.S.A. 101(22):8313-8318(2004) Manabe, S., et al. Biochem. Biophys. Res. Commun. 316(1):218-225(2004)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.