CB018 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q8N357 |
Other Accession | NP_060347.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 40214 Da |
Antigen Region | 329-358 aa |
Gene ID | 54978 |
---|---|
Other Names | Solute carrier family 35 member F6, ANT2-binding protein, ANT2BP, Transport and Golgi organization 9 homolog, SLC35F6, C2orf18 |
Target/Specificity | This CB018 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from the C-terminal region of human CB018. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CB018 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SLC35F6 |
---|---|
Synonyms | C2orf18 |
Function | Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter. |
Cellular Location | Mitochondrion. Lysosome membrane; Multi-pass membrane protein |
Tissue Location | Expressed in pancreatic ductal adenocarcinoma (PDAC) (at protein level). Strongly expressed in prostate and thyroid Weakly expressed in lung, heart, liver and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
The exact function of C2orf18 remains unknown. It contains 1 DUF6 domain.
References
Kashiwaya, K., et al. Cancer Sci. 100(3):457-464(2009)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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