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ADORA2A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | P29274 |
| Other Accession | P30543, Q60613, NP_000666.2 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 44707 Da |
| Antigen Region | 273-301 aa |
| Gene ID | 135 |
|---|---|
| Other Names | Adenosine receptor A2a, ADORA2A, ADORA2 |
| Target/Specificity | This ADORA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the Central region of human ADORA2A. |
| Dilution | IF~~1:10~50 WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ADORA2A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADORA2A |
|---|---|
| Synonyms | ADORA2 |
| Function | Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P30543}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P30543} Note=Colocalizes with GAS2L2 at neuronal processes {ECO:0000250|UniProtKB:P30543} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ADORA2A is a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. This protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
References
Buira, S.P., et al. J. Neurochem. 115(1):283-295(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rogers, P.J., et al. Neuropsychopharmacology 35(9):1973-1983(2010)
Tebano, M.T., et al. ScientificWorldJournal 10, 1768-1782 (2010) :
Kobayashi, H., et al. Behav Brain Funct 6, 50 (2010) :
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