CD1C
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, E |
---|---|
Primary Accession | P29017 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2A7C11 |
Isotype | Mouse IgG2b |
Calculated MW | 37.7kDa |
Immunogen | Purified recombinant fragment of human CD1C (AA: extra 18-302) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 911 |
---|---|
Other Names | R7; CD1; CD1A; BDCA1 |
Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 IHC~~1/200 - 1/1000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CD1C is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD1C |
---|---|
Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein Lysosome. Note=Subject to intracellular trafficking between the cell membrane and endosomes |
Tissue Location | Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1266-75.2.J Exp Med. 2014 Jun 30;211(7):1363-77.
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