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CD1C

Purified Mouse Monoclonal Antibody

     
  • E - CD1C AO2732a
    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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  • WB - CD1C AO2732a
    Figure 2:Western blot analysis using CD1C mAb against human CD1C (AA: extra 18-302) recombinant protein. (Expected MW is 58.1 kDa)
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  • WB - CD1C AO2732a
    Figure 3:Western blot analysis using CD1C mAb against HEK293 (1) and CD1C (AA: extra 18-302)-hIgGFc transfected HEK293 (2) cell lysate.
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  •  - CD1C AO2732a
    Figure 4:Flow cytometric analysis of Ramos cells using CD1C mouse mAb (green) and negative control (red).
    detail
  • IHC - CD1C AO2732a
    Figure 5:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CD1C mouse mAb with DAB staining.
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  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, ICC, E
Primary Accession P29017
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3G1B3
Isotype Mouse IgG2b
Calculated MW 37.7kDa
Immunogen Purified recombinant fragment of human CD1C (AA: extra 18-302) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 911
Other Names R7; CD1; CD1A; BDCA1
Dilution E~~ 1/10000
WB~~ 1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD1C is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD1C
Function Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Cellular Location Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein Lysosome. Note=Subject to intracellular trafficking between the cell membrane and endosomes
Tissue Location Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues
Research Areas
Citations (0)
citation

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References

1.Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1266-75.2.J Exp Med. 2014 Jun 30;211(7):1363-77.

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$ 385.00
Cat# AO2732a
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