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GRIK3
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | Q13003 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2B4H1 |
| Isotype | Mouse IgG1 |
| Calculated MW | 104kDa |
| Immunogen | Purified recombinant fragment of human GRIK3 (AA: extra 32-173) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 2899 |
|---|---|
| Other Names | EAA5; GLR7; GLUR7; GluK3; GluR7a |
| Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GRIK3 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRIK3 |
|---|---|
| Synonyms | GLUR7 |
| Function | Ionotropic glutamate receptor that functions as a cation- permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:7719709). In association with GRIK2, involved in presynaptic facilitation of glutamate release at hippocampal mossy fiber synapses (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P42264}; Multi-pass membrane protein. Postsynaptic cell membrane {ECO:0000250|UniProtKB:P42264}; Multi-pass membrane protein |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
1.Eur Addict Res. 2013;19(1):55-9.2.Psychiatr Pol. 2011 May-Jun;45(3):325-35.
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$ 385.00
Cat# AO2621a
Ordering Information
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