ALDOA
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, E |
---|---|
Primary Accession | P04075 |
Reactivity | Human, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 1C5B2 |
Isotype | Mouse IgG2a |
Calculated MW | 39.4kDa |
Immunogen | Purified recombinant fragment of human ALDOA (AA: 9-145) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 226 |
---|---|
Other Names | ALDA; GSD12; HEL-S-87p |
Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 IHC~~ 1/200 - 1/1000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ALDOA is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ALDOA (HGNC:414) |
---|---|
Synonyms | ALDA |
Function | Catalyzes the reversible conversion of beta-D-fructose 1,6- bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis (PubMed:14766013). In addition, may also function as scaffolding protein (By similarity). |
Cellular Location | Cytoplasm, myofibril, sarcomere, I band {ECO:0000250|UniProtKB:P00883}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:P00883}. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+) {ECO:0000250|UniProtKB:P00883} |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Cancer Lett. 2016 Apr 28;374(1):127-35. 2.Oncol Rep. 2014 Nov;32(5):2031-7.
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