GRIK4
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, ICC, E |
---|---|
Primary Accession | Q16099 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 8H5G5 |
Isotype | Mouse IgG2b |
Calculated MW | 107.2kDa |
Immunogen | Purified recombinant fragment of human GRIK4 (AA: extra 21-166) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 2900 |
---|---|
Other Names | KA1; EAA1; GRIK; GluK4 |
Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 ICC~~ 1/200 - 1/1000 IHC~~ 1/200 - 1/1000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GRIK4 is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GRIK4 |
---|---|
Synonyms | GRIK |
Function | Ionotropic glutamate receptor that functions as a cation- permeable ligand-gated ion channel. Cannot form functional channels on its own (PubMed:8263508). Shows channel activity only in heteromeric assembly with GRIK1, GRIK2 and GRIK3 subunits (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q8BMF5}; Multi-pass membrane protein. Presynaptic cell membrane {ECO:0000250|UniProtKB:Q8BMF5}; Multi-pass membrane protein |

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Provided below are standard protocols that you may find useful for product applications.
References
1.Pharmacogenomics. 2014 Aug;15(11):1451-9.2.Am J Med Genet B Neuropsychiatr Genet. 2012 Jan;159B(1):21-9.

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