GRIN3B
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, E |
---|---|
Primary Accession | O60391 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2A8E11 |
Isotype | Mouse IgG2a |
Calculated MW | 113kDa |
Immunogen | Purified recombinant fragment of human GRIN3B (AA: 135-276) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 116444 |
---|---|
Other Names | NR3B; GluN3B |
Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GRIN3B is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GRIN3B |
---|---|
Function | NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane Note=Requires the presence of GRIN1 to be targeted at the plasma membrane. |
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Provided below are standard protocols that you may find useful for product applications.
References
1.PLoS One. 2015 Mar 13;10(3):e0116319.2.Psychiatry Res. 2014 Aug 30;218(3):356-8.
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