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> home > Products > Primary Antibodies > Antibody Collections > SARS-Human interaction partners > Mouse Monoclonal Antibody to ADIPOQ
Mouse Monoclonal Antibody to ADIPOQ
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | Q15848 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 1E10D5 |
| Isotype | Mouse IgG1 |
| Calculated MW | 26.4kDa |
| Description | This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.; |
| Immunogen | Purified recombinant fragment of human ADIPOQ (AA: 16-154) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application Note | ELISA: 1/10000 WB: 1/500 - 1/2000 FCM: 1/200 - 1/400 |
| Gene ID | 9370 |
|---|---|
| Other Names | ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Monoclonal Antibody to ADIPOQ is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADIPOQ |
|---|---|
| Function | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |
| Cellular Location | Secreted. |
| Tissue Location | Synthesized exclusively by adipocytes and secreted into plasma. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
1.Oncotarget. 2015 Oct 13;6(31):32205-11. ; 2.Clin Biochem. 2015 Sep;48(13-14):860-5. ;
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$ 385.00
Cat# AO2493a
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