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> home > Products > Primary Antibodies > Antibody Collections > Mitochondrion > Mouse Monoclonal Antibody to SOD2
Mouse Monoclonal Antibody to SOD2
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, FC, ICC, E |
|---|---|
| Primary Accession | P04179 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 8H3D2 |
| Isotype | Mouse IgG1 |
| Calculated MW | 24.7kDa |
| Description | This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.; |
| Immunogen | Purified recombinant fragment of human SOD2 (AA: 1-222) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application Note | ELISA: 1/10000 WB: 1/500 - 1/2000 IHC: 1/200 - 1/1000 ICC: 1/50 - 1/250 FCM: 1/200 - 1/400 |
| Gene ID | 6648 |
|---|---|
| Other Names | IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Monoclonal Antibody to SOD2 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SOD2 |
|---|---|
| Function | Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. |
| Cellular Location | Mitochondrion matrix. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
1.Dis Markers. 2015;2015:746329. ; 2.Free Radic Biol Med. 2015 Dec;89:379-86.;
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$ 385.00
Cat# AO2423a
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