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> home > Products > Primary Antibodies > Antibody Collections > B cell receptor signaling > Mouse Monoclonal Antibody to DAPP1
Mouse Monoclonal Antibody to DAPP1
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | Q9UN19 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2F7A9 |
| Isotype | Mouse IgG1 |
| Calculated MW | 32.2kDa |
| Description | DAPP1 (Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides) is a Protein Coding gene. Among its related pathways are Immune System and Downstream signaling events of B Cell Receptor (BCR). GO annotations related to this gene include phospholipid binding and phosphatidylinositol-3,4-bisphosphate binding.; |
| Immunogen | Purified recombinant fragment of human DAPP1 (AA: 127-276) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application Note | ELISA: 1/10000 WB: 1/500 - 1/2000 FCM: 1/200 - 1/400 |
| Gene ID | 27071 |
|---|---|
| Other Names | BAM32 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Monoclonal Antibody to DAPP1 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DAPP1 |
|---|---|
| Synonyms | BAM32 |
| Function | May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K. |
| Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation |
| Tissue Location | Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
1.J Immunol. 2011 Oct 15;187(8):3972-8. ; 2.J Immunol. 2004 Nov 1;173(9):5601-9.;
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$ 385.00
Cat# AO2369a
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