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NES Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | P48681 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 1A9G12 |
| Isotype | IgG1 |
| Calculated MW | 177kDa |
| Description | This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. |
| Immunogen | Purified recombinant fragment of human NESTIN (AA: 419-588 ) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 10763 |
|---|---|
| Other Names | Nestin, NES |
| Dilution | E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NES Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NES |
|---|---|
| Function | Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen- stimulated proliferation of neural progenitor cells (By similarity). |
| Tissue Location | CNS stem cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
1.Neoplasma. 2012;59(3):310-5.2.Eur J Histochem. 2011 Nov 14;55(4):e39.
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