NES Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
---|---|
Primary Accession | P48681 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 1A9G12 |
Isotype | IgG1 |
Calculated MW | 177kDa |
Description | This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. |
Immunogen | Purified recombinant fragment of human NES (AA: 419-588 ) expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Gene ID | 10763 |
---|---|
Other Names | Nestin, NES |
Dilution | E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | NES Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NES |
---|---|
Function | Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen- stimulated proliferation of neural progenitor cells (By similarity). |
Tissue Location | CNS stem cells. |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Neoplasma. 2012;59(3):310-5. 2.Eur J Histochem. 2011 Nov 14;55(4):e39.
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