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RND3 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, FC, ICC, E |
|---|---|
| Primary Accession | P61587 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 5C7E8 |
| Isotype | IgG1 |
| Calculated MW | 27.4kDa |
| Description | This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Immunogen | Purified recombinant fragment of human RND3 (AA: 104-241) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 390 |
|---|---|
| Other Names | Rho-related GTP-binding protein RhoE, Protein MemB, Rho family GTPase 3, Rho-related GTP-binding protein Rho8, Rnd3, RND3, ARHE, RHO8, RHOE |
| Dilution | E~~1/10000 WB~~1/500 - 1/2000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RND3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RND3 |
|---|---|
| Synonyms | ARHE, RHO8, RHOE |
| Function | Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. |
| Cellular Location | Golgi apparatus membrane; Peripheral membrane protein |
| Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Hepatology. 2013 Jan;57(1):152-61. 2.Oncol Rep. 2011 Jan;25(1):173-80.
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