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Bpifa2 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, FC, E |
|---|---|
| Primary Accession | P07743 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2B4F5 |
| Isotype | IgG1 |
| Calculated MW | 24.8kd |
| Description | Bpifa2 has strong antibacterial activity against P. aeruginosa. |
| Immunogen | Purified recombinant fragment of mouse mSplunc2 (AA: 16-169) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
| Gene ID | 19194 |
|---|---|
| Other Names | BPI fold-containing family A member 2, Parotid secretory protein, PSP, Bpifa2, Psp |
| Dilution | E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Bpifa2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Bpifa2 |
|---|---|
| Synonyms | Psp |
| Function | Has strong antibacterial activity against P. aeruginosa. |
| Cellular Location | Secreted. |
| Tissue Location | Predominates in the parotid glands, present in smaller amounts (1/10) in the submaxillary glands and in the sublingual glands, and at lower amount in the pancreas but undetectable in the liver. Found also in lacrimal gland. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. ; ;
References
1.Am J Physiol. 1997 Apr;272(4 Pt 1):G863-71.2.Nucleic Acids Res. 1998 Jun 1;26(11):2761-70.
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