Bpifa2 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, E |
---|---|
Primary Accession | P07743 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 3F8E4 |
Isotype | IgG1 |
Calculated MW | 24.8kDa |
Description | Bpifa2 has strong antibacterial activity against P. aeruginosa. |
Immunogen | Purified recombinant fragment of mouse mSplunc2 (AA: 16-169) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Gene ID | 19194 |
---|---|
Other Names | BPI fold-containing family A member 2, Parotid secretory protein, PSP, Bpifa2, Psp |
Dilution | E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Bpifa2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Bpifa2 |
---|---|
Synonyms | Psp |
Function | Has strong antibacterial activity against P. aeruginosa. |
Cellular Location | Secreted. |
Tissue Location | Predominates in the parotid glands, present in smaller amounts (1/10) in the submaxillary glands and in the sublingual glands, and at lower amount in the pancreas but undetectable in the liver. Found also in lacrimal gland. |
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Background
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene. ;
References
1.Am J Physiol. 1997 Apr;272(4 Pt 1):G863-71.2.Nucleic Acids Res. 1998 Jun 1;26(11):2761-70.
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