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ACP5 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | P13686 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 5C5E7 |
| Isotype | IgG1 |
| Calculated MW | 36.6kDa |
| Description | This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. |
| Immunogen | Purified recombinant fragment of human ACP5 (AA: 221-325) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 54 |
|---|---|
| Other Names | Tartrate-resistant acid phosphatase type 5, TR-AP, 3.1.3.2, Tartrate-resistant acid ATPase, TrATPase, Type 5 acid phosphatase, ACP5 |
| Dilution | E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ACP5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ACP5 |
|---|---|
| Function | Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T- cell leukemias. |
| Cellular Location | Lysosome. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. ;
References
1. Clin Chim Acta. 2011 May 12;412(11-12):963-9. 2. Eur J Gynaecol Oncol. 2011;32(6):615-8.
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