SST Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, E |
---|---|
Primary Accession | P61278 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 7G5 |
Isotype | IgG1 |
Calculated MW | 12.7kDa |
Description | The preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. |
Immunogen | Purified recombinant fragment of human SST (AA: 1-116) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 6750 |
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Other Names | Somatostatin, Growth hormone release-inhibiting factor, Somatostatin-28, Somatostatin-14, SST |
Dilution | E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SST Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SST |
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Function | [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. |
Cellular Location | Secreted {ECO:0000250|UniProtKB:P60042}. |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Acta Neurol Scand. 2010 Apr;121(4):225-9.2.Endocrinology. 2009 May;150(5):2254-63.
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