KID Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, E |
---|---|
Primary Accession | Q14807 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 1E3 |
Isotype | IgG1 |
Calculated MW | 73kDa |
Description | The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. |
Immunogen | Purified recombinant fragment of human KID expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Gene ID | 3835 |
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Other Names | Kinesin-like protein KIF22, Kinesin-like DNA-binding protein, Kinesin-like protein 4, KIF22, KID, KNSL4 |
Dilution | E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 FC~~1/200 - 1/400 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | KID Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KIF22 |
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Synonyms | KID, KNSL4 |
Function | Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA (By similarity). Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells (PubMed:25743205). |
Cellular Location | Nucleus. Cytoplasm, cytoskeleton |
Tissue Location | Expressed in bone, cartilage, joint capsule, ligament, skin, and primary cultured chondrocytes |
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Provided below are standard protocols that you may find useful for product applications.
References
1. Cell. 2008 Mar 7;132(5):771-82. 2. Retrovirology. 2009 May 19;6:47.
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