OTX2 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC, E |
---|---|
Primary Accession | P32243 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 1H12C4B5 |
Isotype | IgG1 |
Calculated MW | 32kDa |
Description | This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development.Tissue specificity: Expressed in brain. |
Immunogen | Purified recombinant fragment of human OTX2 expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Gene ID | 5015 |
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Other Names | Homeobox protein OTX2, Orthodenticle homolog 2, OTX2 |
Dilution | E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | OTX2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OTX2 |
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Function | Transcription factor probably involved in the development of the brain and the sense organs. Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
References
1. Hum Mutat. 2008 Nov;29(11):E278-83. 2. Cancer Res. 2010 Jan 1;70(1):181-91.
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