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APOL1 Antibody

Purified Mouse Monoclonal Antibody

     
  • WB - APOL1 Antibody AO1256a
    Figure 1: Western blot analysis using APOL1 mouse mAb against human plasma (1).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O14791
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1D4
Isotype IgG1
Calculated MW 44kDa
Description APOL1(apolipoprotein L, 1), also known as APOL, APO-L, APOL-I. Entrez Protein NP_001130012. It is a 395aa secreted high density lipoprotein which binds to apolipoprotein A-I. And is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.
Immunogen Purified recombinant fragment of APOL1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 8542
Other Names Apolipoprotein L1, Apolipoprotein L, Apo-L, ApoL, Apolipoprotein L-I, ApoL-I, APOL1, APOL
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAPOL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APOL1
Synonyms APOL
Function May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
Cellular Location Secreted.
Tissue Location Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen
Research Areas
Citations (0)
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References

1. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4118-23. 2. J Lipid Res. 2005 Mar;46(3):469-74.

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$ 385.00
Cat# AO1256a
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