FABP4 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P15090 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 5H11A4E11 |
Isotype | IgG1 |
Calculated MW | 14719 Da |
Description | FABP4: fatty acid binding protein 4, adipocyte. FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. |
Immunogen | Purified recombinant fragment of FABP4 (aa61-121) expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Gene ID | 2167 |
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Other Names | Fatty acid-binding protein, adipocyte, Adipocyte lipid-binding protein, ALBP, Adipocyte-type fatty acid-binding protein, A-FABP, AFABP, Fatty acid-binding protein 4, FABP4 |
Dilution | WB~~1/500 - 1/2000 IHC~~1:200~~1000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FABP4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FABP4 |
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Function | Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P04117}. Nucleus {ECO:0000250|UniProtKB:P04117}. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export. {ECO:0000250|UniProtKB:P04117} |
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Provided below are standard protocols that you may find useful for product applications.
References
1. J Biol Chem. 2004 Dec 10;279(50):52399-405. 2. Mol Cell Proteomics. 2005 Apr;4(4):570-81.
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