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> home > Products > Primary Antibodies > Signal Transduction > Anti-Caveolin-1 (Tyr-14), Phosphospecific Antibody
Anti-Caveolin-1 (Tyr-14), Phosphospecific Antibody
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Application 
| WB |
|---|---|
| Primary Accession | Q03135 |
| Reactivity | Bovine |
| Host | Mouse |
| Clonality | Mouse Monoclonal |
| Isotype | IgG1 |
| Clone Names | M283 |
| Calculated MW | 20472 Da |
| Gene ID | 857 |
|---|---|
| Other Names | caveolin1, vip21 |
| Target/Specificity | Caveolins are the primary structural components of the plasma membrane microdomains, caveolae. Three members of the caveolin family (caveolin-1, -2, and -3) have been identified, and each has distinct expression patterns. Caveolins are involved in diverse biological functions, including vesicular trafficking, cholesterol homeostasis, cell adhesion and apoptosis. Caveolins can interact with various signaling molecules, including G-proteins, receptor tyrosine kinases, PKCs, and Src family kinases. Phosphorylation at Tyr-14 is essential for caveolin association with SH2 or PTB domain-containing adaptor proteins, while phosphorylation at Ser-80 regulates caveolin binding to the ER membrane and entry into the secretory pathway. |
| Format | Protein A Purified |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Anti-Caveolin-1 (Tyr-14), Phosphospecific Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Shipping | Blue Ice |
Research Areas
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$ 360.00
Cat# AN1687
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